Bibliocafe
Near the joy ride cafe got mixed drinks at moderate prices. also one of the few places in sucre to serve taquina amber, one of bolivia's best brews. plays classic rock and pop. also serves food. there are actually two bibliocafes: bibliocafe is more relaxed and intimate; bibliocafe 'concert' has some live music and is more energetic.
Florin
Nightly happy hour from 9.30 to 10.30 sees two-for-one drinks and a regular crowd. Has thumping events from time to time. Particularly popular with locals and the resident gringo population.
Joy Ride Cafe
(http://www.joyridebol.com/), calle nicolas ortiz 14, is also a good place at night. it's popular with the more wealthy bolivians as well as travellers. the food, though, is sub-par and hot drinks are best avoided if you like them hot.
Tabaco´s Soul
Plays rock. Check your bill! great mixdrinks served in pitchers. cheap and very social
Most places on the main square, and down the first block of Calle Nicolas Ortiz, are heavily gringofied, -for better or worse. Sunday is by far the slowest night.
In the market there are many stalls selling all kinds of fruit juices and salads. Particularly recommended is the multi-vitaminico, a mix of basically everything in the stall - cereales, fruits, vegetables, and sometimes egg, beer, honey etc - which is a great pre-hike breakfast or a great post-drinking pick-me-up.
La Posada
Just a few steps from the main square the hotel La Posada offers every sunday a nice buffet that is worth the 40 Bs. because of the vegetarian parts. Starts at 12:00, dont be too late, since it can be crowded.
El Alfarero
University students run a cheap and cosy cafe with some board games and pingpong table. Also screens films. Students receive a discount.
Stigma
Biggest club in town, -young crowd. Fills up at 2 AM.
Alaska
Karaoke upstairs, and dance floor down.
Menfis
Warm up venue for young locals on weekends.